Study of occurrence of HBeAg among Hepatitis- B surface antigen positive cases

Original Article

Author Details : Pragati Devi, Shweta R Sharma*, Amit Mishra, Umar Farooq, Sudhir Singh, Vasundhara Sharma, Imran Ahamad

Volume : 7, Issue : 4, Year : 2021

Article Page : 269-273

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Introduction: Hepatitis is a universal concept that mean inflammation of the liver and infection with 1 of the 5 viruses called hepatitis A, B, C, D and E viruses is the almost common cause. The 5 viral cause’s hepatitis-B infection is the worldly almost common hepatic infection, which is cause by hepatitis-B (HBV). HBV is a DNA virus. It is 42–47 nm in diameter and enters the liver through with blood stream. HBV is highly contagious and is 60–100 times more than HIV. It is transmissible throughly with blood cell and all body fluid or mucosa membranous. It is transmitted almost normally by unsafe physical sexual contact, contaminated blood transfusions and unsterilized use needles from mother to baby, close household touch and in the midst of children in early childhood.
Aim & Objective: Study of occurrence of HBeAg among Hepatitis- B surface antigen positive cases; 1. Identification of Hepatitis B Surface Antigen positive cases; 2. Occurrence of HBeAg among Hepatitis- B surface antigen positive cases.
Material and Methods: 5ml blood was collected from anterior cubital vein by Venipuncture from recruited patient. Samples were collected after proper consent and aseptic precautions. Then every blood sample was transfer overhead a tagged tube plane vial
Observation & Result: The study was conducted in Department of Microbiology, Teerthanker Mahaveer Hospital. Blood sample from 106 patients including both male and female were collected from various department of the Hospital for the analysis purpose. Out of them, 38 (36%) cases were HBeAg positive and 68 (64%) cases were HBeAg negative
Conclusion : The result of our study put up valuable information and connection in HBeAg positive cases. In this little sample size 106 analysis of the patients at Uttar Pradesh Teerthanker Mahaveer Medical College, the prevalence of HBeAg (positive results) in the department of medical microbiology, while the negative result is 68(64%).Males 29(76%) were more affected by the HBV (HBeAg) infection as compare to Female 9(24%).An important preventive measure is the screening for HBV in blood donors. Hepatitis-B related chronic liver disease and hepatocellular carcinoma are best prevented by universal childhood immunization. In non-infected people, HBV infection can be avoided by HBV vaccination.Injections Sequence 3 at 0, 1 and 6 months. In over 90% of recipients vaccination is successful.
Keywords: Fever, Headache, Jaundice, Abdominal pain, Vomiting, Fatigue, Joint pain, Nausea

How to cite : Devi P, Sharma S R, Mishra A, Farooq U, Singh S, Sharma V, Ahamad I, Study of occurrence of HBeAg among Hepatitis- B surface antigen positive cases. IP Int J Med Microbiol Trop Dis 2021;7(4):269-273

Copyright © 2021 by author(s) and IP Int J Med Microbiol Trop Dis. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (

Article History

Received : 04-08-2021

Accepted : 16-08-2021

Available online : 18-11-2021

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